PUBLICATIONS
Wong-Rolle A, Dong Q, Zhu Y, Divakar P, Hor JL, Kedei N, Wong M, Tillo D, Conner EA, Rajan A, Schrump DS, Jin C, Germain R, Zhao C. Spatial meta-transcriptomics reveal associations of intratumor bacteria burden with lung cancer cells showing a distinct oncogenic signature. (2022) Journal for ImmunoTherapy of Cancer. Vol. 10 Issue 7: e004698.
Dong Q, Chen ES, Zhao C, Jin C*. Host-Microbiota Interaction in Lung Cancer. (2021) Frontiers in Immunology. *Corresponding author.
Wong-Rolle A, Wei H, Zhao C, Jin C*. (2020) Unexpected guest in the tumor microenvironment: microbiome in cancer. Protein & Cell. *Corresponding author.
Hu B*, Jin C*, Zeng X* et al. γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis. Nature. 578, 610–614 (2020). https://www.nature.com/articles/s41586-020-2028-z *Equal contribution.
Jin C, Lagoudas G, Zhao C, Bullman S, Bhutkar A, Hu B, Mazzilli S, Ameh S, Sandel D, Liang X, Whary M, Meyerson M, Germain R, Blainey P, Fox J, Jacks T. Commensal microbiota promote lung cancer development via γδ T cells. (2019), Cell. 176: 1–16
See highlights of our story at:
Nature Reviews Cancer: https://www.nature.com/articles/s41568-019-0122-z
Cancer Discovery: http://cancerdiscovery.aacrjournals.org/content/early/2019/02/13/2159-8290.CD-NB2019-019
Science Translational Medicine: http://stm.sciencemag.org/content/11/480/eaaw5330
MIT News: http://news.mit.edu/2019/bacteria-promote-lung-tumor-development-0131
Hu B*, Jin C*, Li HB*, Tong J, Ouyang X, Zhu S, Strowig T, Lam FC, Zhao C, Henao-Mejia J, Fitzgerald KA, Eisenbarth SC, Elinav E, Flavell RA. (2016) The DNA sensing Aim2 inflammasome controls radiation induced cell death and tissue injury. Science. 354(6313):765-768. *Equal contribution.
Henao-Mejia J*, Elinav E*, Jin C*, Hao L, Mehal WZ, Strowig T, Thaiss CA, Kau AL, Eisenbarth SC, Jurczak MJ, Camporez JP, Shulman GI, Gordon JI, Hoffman HM, Flavell RA. (2012) Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature. 482(7384): 179-85. *Equal contribution.
Jin C, Frayssinet P, Pelker R, Cwirka D, Hu B, Vignery A, Eisenbarth SC, Flavell RA. (2011) NLRP3 inflammasome plays a critical role in the pathogenesis of hydroxyapatite-associated arthropathy. Proceedings of the National Academy of Sciences USA (PNAS). 108(36): 14867-72.
Li HB*, Jin C*, Chen Y, Flavell RA. (2014) Inflammasome activation and metabolic disease progression. Cytokine & Growth Factor Reviews. 25(6): 699-706. Review. *Equal contribution.
Elinav E*, Nowarski R*, Thaiss C*, Hu B*, Jin C*, Flavell RA. (2013) Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms. Nature Reviews Cancer. 13(11): 759-71. Review. *Equal contribution.
Jin C, Flavell RA. (2013) Innate sensors of pathogen and stress: linking inflammation to obesity. Journal of Allergy and Clinical Immunology. 132(2): 287-94. Review
Jin C, Henao-Mejia J, Flavell RA. (2013) Innate immune receptors: key regulators of metabolic diseases progression. Cell Metabolism. 17(6): 873-82. Review
Jin C, Flavell RA. (2010) Molecular mechanism of NLRP3 inflammasome activation. Journal of Clinical Immunology. 30(5): 628-31. Review.
Jin C, Flavell RA. (2010) Inflammasome activation. The missing link: how the inflammasome senses oxidative stress. Immunol Cell Biol. 88(5): 510-2
Hu B, Elinav E, Huber S, Strowig T, Hao L, Hafemann A, Jin C, Eisenbarth SC, Flavell RA. Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer. (2013) Proceedings of the National Academy of Sciences USA (PNAS). 110(24): 9862-9867.
Hu B, Elinav E, Huber S, Booth CJ, Strowig T, Jin C, Eisenbarth SC, Flavell RA. (2010) Inflammation- induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. Proceedings of the National Academy of Sciences USA (PNAS). 107(50): 21635-40.
Wang Q, Huang Z, Xue H, Jin C, Ju XL, Han JD, Chen YG. (2008) MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4. Blood. 111(2): 588-95.